CRM-Zero-Mus
Control Mussel Tissue Certified Reference Material for Marine Toxins
Intended Use
CRM-Zero-Mus is a mussel tissue (Mytilus edulis) matrix CRM intended for use as a negative control for the analysis of shellfish toxins. It is free of the following toxins: paralytic shellfish toxins (PSTs), domoic acid (DA) and its isomers, okadaic acid (OA) and dinophysistoxins (DTXs), azaspiracids (AZAs), yessotoxins (YTXs), pectenotoxins (PTXs) and gymnodimine (GYM). It is suited for use in testing analytical procedures for selectivity, spike recovery and matrix matched calibration. CRM-Zero- Mus is not suitable as a negative control for spirolides (SPXs) and pinnatoxins (PnTXs) because these toxins are present, albeit at very low levels.
Table 1a: Concentration values for paralytic shellfish toxins in CRM-Zero-Mus were determined following an acidic extraction and analysis by LC-pcox-FLD [1]. Quantitation was performed relative to NRC certified calibration solutions or in-house prepared standards (nd = not detected).
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