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Nodularin
Product Description
Inhibitor of protein phosphatase 1 (PP1) (IC50=1.8nM),
protein phosphatase 2A (PP2A) (IC50=0.026nM) and to a lesser extent
protein phosphatase 2B (PP2B) (IC50=8.7μm). Similar to microcystin-LR
(Prod. No. 350-012) but with increased water solubility.
Product Specific Literature References
Nodularin, microcystin and the configuration of Adda:
K.L. Rinehart, et al.; JACS 110, 8557 (1988)Inhibition of protein
phosphatases by microcystins and nodularin associated with hepatotoxicity:
S. Yoshizawa, et al.; J. Cancer Res. Clin. Oncol. 116, 609 (1990)
Abstract<B< td>
RELATED PRODUCT GROUPS
Signal Transduction & Cell Trafficking > Protein
Phosphatases [PP]/Related Products > PP1 Inhibitors / Signal
Transduction & Cell Trafficking > Protein Phosphatases [PP]/Related
Products > PP2 Inhibitors / Enzyme Inhibitors / Natural Products
产品编号：350-061-C010
产品名称：Nodularin
产品规格：10 μg
长期贮藏温度：-20°C
纯度：>=96%
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